Pathophysiology and Spectrum of Neuro-COVID
DOI:
https://doi.org/10.47310/iarjmsr.2021.V02i01.01Keywords:
COVID-19, neurological, SARS-CoV-2, brain, nerves.Abstract
Some neurological manifestations may not be specific for COVID-19 and due to other causes but that COVID-19 must be considered as a differential of all acute neurological conditions. The following neuropathological abnormalities were found: acute microscopic thrombotic ischemic infarcts; microscopic haemorrhagic infarcts; petechial haemorrhage; focal perivascular parenchymal Tcell infiltrates; diffuse perivascular parenchymal T-cell infiltrates; leptomeningeal inflammation; interstitial brainstem inflammation with neuronal loss; capillary endothelium expression of ACE2 receptors; microglial nodules; and hypoxic ischemia changes and neuronal loss.