Background: Cervical cancer is primarily caused by persistent infection with high-risk human papillomavirus (HPV) types. In rural areas, factors such as poor hygiene, early marriage, and inadequate healthcare access contribute to higher incidence and mortality rates. Despite being preventable through screening and vaccination, the disease continues to pose challenges in underserved regions. Methods: This cross-sectional study was conducted in rural Bangladesh, involving 450 participants aged more than 30 years up to 59 years selected via stratified random sampling. Data were collected through structured interviews, clinical assessments, and review of health records to identify sociodemographic, reproductive, and healthcare-related risk factors. Interventions, including HPV vaccination and education campaigns, were implemented, followed by evaluations to assess their effectiveness. Results:  The study revealed significant risk factors, including HPV infection (20%), early marriage (44.4%), poor hygiene (55.6%), and limited access to healthcare (66.7%). Targeted interventions led to increased awareness, improved screening participation, and a reduction in HPV prevalence. Conclusion: This study highlights the urgent need for community-based strategies to address cervical cancer disparities in rural populations.