Background: Premature rupture of membranes (PROM) affects 4% to 10% of full-term pregnancies globally. PROM accounts for roughly one third of all preterm births. Aim: To find out the feto-maternal outcome of Premature Rupture of Membrane with it’s risk factors. Methods: It was a hospital based prospective study conducted in the Department of Obstetrics and Gynecology in Dinajpur Medical College & Hospital, Dinajpur. Study participants were 50 admitted patients with Pre-mature Rupture of Membrane (PROM) in the Obstetrics and Gynecology Department. Data was collected by a checklist and structured Bangla questionnaire and analysis was done by using SPSS version 20. Results: Majority of PROM patients belonged to the age group 21-24 years which was 19 (38.0%). The mean (±SD) age of the patients was 26.04±5.2 years. A total of 35 (70.0%) patients delivered within 24 hours of rupture of membrane and 9 patients (56.2%) had past history of MR or abortion, 3 (18.8%) had history of PROM in previous pregnancy. A total of 23 (46.0%) cases had sexual contact within 1 week of rupture of membranes. E.Coli was the most common pathogen 5 (41.7%) associated with positive High vaginal Swab (HVS) culture. Majority of the patients 31 (62.0%) developed labour pain within 12 hours of PROM. Sixteen (32.0%) patients developed morbidity included puerperal sepsis, UTI, PPH, wound dehiscence, and retained placenta. APGAR score at 5 minutes was >7 in 30 (60%) babies. Out of 47 alive babies. 19 (40.4%) were affected by the consequences of PROM and birth process. Among them asphyxia was more common 7 (35%) than other morbidities. Total 10 of them required admission in neonatal ward and most of the morbidity of the newborn appeared within 1 to 3 days of delivery. Conclusion: Early identification and management of PROM can reduce negative feto-maternal outcomes.